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JoVE Journal Bioengineering
Transplante de islotes en el cojín de grasa epididimal de ratones diabéticos
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Transplante de islotes en el cojín de grasa epididimal de ratones diabéticos

Article DOI: 10.3791/54995-v • 11:58 min • July 23rd, 2017
July 23rd, 2017 •
*1, *1, *2, 2, 1
1Department of Biomedical Engineering, Peking University, 2Institute of Molecular Medicine, Peking University
* These authors contributed equally

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Este protocolo demuestra el aislamiento de los islotes murinos y la siembra en un andamio decelularizado. Los islotes soportados por el andamio fueron trasplantados en la almohadilla de grasa epididimal de ratones diabéticos inducidos por estreptozotocina (STZ). Los islotes sobrevivieron en el sitio del trasplante e invirtieron la condición hiperglucémica.

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Bioingeniería Número 125 aislamiento de islotes andamiaje trasplante almohadilla de grasa epididimal murino diabetes
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