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JoVE Journal Cancer Research
Test af Vascular Invasiv evne kræftceller i Zebrafisk (
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Test af Vascular Invasiv evne kræftceller i Zebrafisk (

Article DOI: 10.3791/55007-v • 07:31 min • November 3rd, 2016
November 3rd, 2016 •
1, 1, 1, 1
1Department of Oncology, Lombardi Comprehensive Cancer Center, Georgetown University

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Denne fremgangsmåde anvender zebrafisk embryoner til effektivt teste den vaskulære invasive evne af cancerceller. Fluorescerende cancerceller injiceres i præcardielt sinus eller blommesæk af fostre. Cancercelle vaskulær invasion og ekstravasation vurderes via fluorescensmikroskopi af halen område 24 til 96 timer senere.

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Cancer Research Cancer Ekstravasation zebrafisk Embryo Fluorescens vaskulær invasion Metastase
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