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JoVE Journal Cancer Research
Ett syngent musmodell av metastaserad njurcellscancer för kvantitativ och Longitudinal Bedömning av Prekliniska terapier
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Ett syngent musmodell av metastaserad njurcellscancer för kvantitativ och Longitudinal Bedömning av Prekliniska terapier

Article DOI: 10.3791/55080-v • 06:38 min • April 12th, 2017
April 12th, 2017 •
*1,2, *1,2,3, 4,5, 1,2,3
1Department of Urology, University of Minnesota, 2Masonic Cancer Center, University of Minnesota, 3Microbiology, Immunology, and Cancer Biology Graduate Program, University of Minnesota, 4Department of Medical Microbiology, Immunology and Cell Biology, Southern Illinois University School of Medicine, 5Simmons Cancer Institute
* These authors contributed equally

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Genomförande av en ortotopisk modell av njurcellscancer i immunkompetenta möss ger utredaren en kliniskt relevanta system definieras av närvaron av en primär njurtumör och lungmetastaser i samma djur. Detta system kan användas för att prekliniskt testa en mängd olika behandlingar in vivo.

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Cancer Research njurcellskarcinom metastas njure ortotopisk intrarenal luciferas
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