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Journal / Immunology and Infection / HDAC 抑制剂介导的 B 细胞 rna 和基因的基因组分析--诱导进行类开关 DNA…
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Immunology and Infection

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JoVE Journal Immunology and Infection
HDAC 抑制剂介导的 B 细胞 rna 和基因的基因组分析--诱导进行类开关 DNA 重组和血浆细胞分化
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HDAC 抑制剂介导的 B 细胞 rna 和基因的基因组分析--诱导进行类开关 DNA 重组和血浆细胞分化

Article DOI: 10.3791/55135-v • 11:06 min • September 20th, 2017
September 20th, 2017 •
1, 1,2, 1,3, 1,3, 1, 1
1Department of Microbiology, Immunology and Molecular Genetics, University of Texas Long School of Medicine at San Antonio, 2Xiangya School of Medicine, Cental South University, 3Greehey Children’s Cancer Research Institute, University of Texas Long School of Medicine at San Antonio

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后生因素可以与基因程序相互作用, 调节基因表达, 调节 B 细胞功能。结合体外b 细胞刺激、qRT PCR、高通量 rna 序列和 mRNA 序列方法, 可以分析 b 细胞中 miRNA 和基因表达的表观遗传调控。

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免疫学 问题 127 B 细胞 类开关 DNA 重组 流式细胞术 组蛋白乙酰 (HDAC) 抑制剂 (助) mrna rna mrna 序列 miRNA-seq 血浆细胞分化
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