JoVE Journal
Medicine
Medicine
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使用仔猪模型研究麻醉诱发的发育神经毒性(AIDN):一种转化神经科学方法
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Article
DOI:
10.3791/55193-v
•
06:38 min
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June 11th, 2017
使用仔猪模型研究麻醉诱发的发育神经毒性(AIDN):一种转化神经科学方法
June 11th, 2017
•
Emmett E. Whitaker1,2, Christopher Z. Zheng1, Bruno Bissonnette1,2,3, Andrew D. Miller4, Tanner L. Koppert1,2, Joseph D. Tobias1,2, Christopher R. Pierson5,6, Fedias L. Christofi1
1Department of Anesthesiology, Ohio State University College of Medicine, 2Department of Anesthesiology and Pain Medicine, Nationwide Children's Hospital, 3Department of Anaesthesia and Critical Care Medicine, University of Toronto, 4Department of Biomedical Sciences, Section of Anatomic Pathology, Cornell University College of Veterinary Medicine, 5Department of Pathology and Anatomy, Ohio State University College of Medicine, 6Department of Pathology and Laboratory Medicine, Nationwide Children's Hospital
Chapters
Summary
Please note that all translations are automatically generated.
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麻醉诱导的发育神经毒性(AIDN)研究集中在啮齿动物,其不广泛适用于人类。非人灵长类动物模型更相关,但成本高昂,难以用于实验。相比之下,仔猪是一种临床相关的实用动物模型,是研究麻醉神经毒性的理想选择。