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Genetics

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JoVE Journal Genetics
Mapping RNA-RNA Interactions Globally Using Biotinylated Psoralen
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Mapping RNA-RNA Interactions Globally Using Biotinylated Psoralen

Article DOI: 10.3791/55255-v • 11:32 min • May 24th, 2017
May 24th, 2017 •
1, 2, 2, 1
1Stem Cell and Regenerative Biology, Genome Institute of Singapore, A*STAR, 2Computational and Systems Biology, Genome Institute of Singapore, A*STAR

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Hier worden we gedetailleerd beschreven over de methode van S- vergelijking van P- soralen verknoopt, L igated en S gekozen H ybrids (SPLASH), die genoom-wide mapping van intramoleculaire en intermoleculaire RNA-RNA interacties in vivo mogelijk maakt . SPLASH kan toegepast worden om RNA-interacties van organismen te bestuderen, waaronder gist, bacteriën en mensen.

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Genetica RNA genomics interactome sequencing structuur human
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