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Developmental Biology

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JoVE Journal Developmental Biology
Brug Primære Neurosfære kulturer til at studere Primær Cilia
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Brug Primære Neurosfære kulturer til at studere Primær Cilia

Article DOI: 10.3791/55315-v • 08:14 min • April 14th, 2017
April 14th, 2017 •
1, 1, 1, 1
1Department of Cell Biology, University of Texas Southwestern Medical Center

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Den primære cilium er fundamentalt vigtigt i neural progenitorcelle proliferation, neuronal differentiering, og voksen neuronal funktion. Her beskriver vi en metode til at studere ciliogenesis og handel med signalproteiner til cilia i neurale stamceller / progenitorceller og differentierede neuroner anvender primære neurosfære-kulturer.

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Developmental Biology primær cilier neurale stamceller neurale progenitorceller neurosfærer sonisk pindsvin G-protein-koblet receptor Gpr161
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