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Journal / Immunology and Infection / Модель переходной трансгенерации IL-8…
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Immunology and Infection

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JoVE Journal Immunology and Infection
Модель переходной трансгенерации IL-8 для
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Модель переходной трансгенерации IL-8 для

Article DOI: 10.3791/55499-v • 08:16 min • July 7th, 2017
July 7th, 2017 •
*1, *2, *3, 3, 4, 5,2, 6, 7, 2, 8, 1
1Department of Medicine, General Pathology Division, Cystic Fibrosis Translational Research Laboratory "D. Lissandrini", University of Verona, 2Corporate Preclinical R&D, Chiesi Farmaceutici S.p.A., 3Department of Diagnostic and Public Health, Microbiology Division, University of Verona, 4Dipartimento di Scienze Medico-Veterinarie, University of Parma, 5Department of Biomedical Biotechnological and Translational Sciences, University of Parma, 6Department of Computer Science, University of Verona, 7Department of Neurological, Biomedical and Movement Sciences, University of Verona, 8Cystic Fibrosis Regional Center (CFC), AOUI Verona
* These authors contributed equally

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Описанный здесь способ позволяет визуализировать активацию IL-8-зависимого воспаления в легких мышей посредством неинвазивной биолюминесцентной визуализации (BLI). Одно и то же животное может быть подвергнуто BLI несколько раз в течение двух месяцев с момента доставки конструкции репортера люциферазы.

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Иммунология выпуск 125 воспаление доставка генов, биолюминесценция интерлейкин-8 легкие
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