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JoVE Journal
Biochemistry

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镍 - 席夫碱的水解复杂环境条件适宜酸不稳定保护基团的保留
 
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镍 - 席夫碱的水解复杂环境条件适宜酸不稳定保护基团的保留

Article DOI: 10.3791/55677-v 06:44 min April 6th, 2017
April 6th, 2017

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Summary

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Click here for the English version.

这里,我们提出一种有效的水解和从镍席夫碱配合物中分离的氨基酸的后续的Fmoc保护。是必需的酸不稳定侧链保护基团的保留时这里介绍的水解条件是适合使用的。这种技术可以适用于各种非天然氨基酸的衬底。

Tags

生物化学,第122,席夫碱,水解,镍,非天然氨基酸,合成,侧链保护基团
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