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Overaccumulation van de Ileectomy-geïnduceerde gal in de darm van de muis
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Overaccumulation van de Ileectomy-geïnduceerde gal in de darm van de muis

Article DOI: 10.3791/55728-v • 06:55 min • August 21st, 2017
August 21st, 2017 •
*1,2,3, 1,2, 1,2, *1,2
1Department of Medicine, Case Cardiovascular Research Institute, Case Western Reserve University, 2Harrington Heart and Vascular Institute, University Hospitals Cleveland Medical Center, 3Institute for Transformative Molecular Medicine, Case Western Reserve University School of Medicine, University Hospitals Cleveland Medical Center
* These authors contributed equally

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Dunne darm-afhankelijke gal zuur reabsorptie en feedback remming van hepatische gal zuur synthese is belangrijk voor systemische homeostase en gezondheid. In deze studie beschrijven we een muismodel voor ileale resectie ileectomy-geïnduceerde gal malabsorptie, overaccumulation, en toxiciteit in de darm van de muis te evalueren.

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Geneeskunde kwestie 126 Ileectomy ziekte muismodel weefsel communicatie fibroblast groeifactor 15 (FGF15) gal zuur reabsorptie short bowel syndroom
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