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JoVE Journal Bioengineering
Metaboliska Glycoengineering av Sialic Acid använder N-acyl-modified Mannosamines
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Metaboliska Glycoengineering av Sialic Acid använder N-acyl-modified Mannosamines

Article DOI: 10.3791/55746-v • 12:06 min • November 25th, 2017
November 25th, 2017 •
1,2, 3
1Max von Pettenkofer-Institut & Genzentrum, Virologie, Nationales Referenzzentrum für Retroviren, Medizinische Fakultät, LMU München, 2Institut für Laboratoriumsmedizin, klinische Chemie und Pathobiochemie, Charité - Universitätsmedizin Berlin, 3Institut für Physiologische Chemie, Martin-Luther-Universität Halle-Wittenberg

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Sialic acid är en typisk monosackarid-enhet finns i Glykokonjugat. Det är involverade i en uppsjö av molekylära och cellulära interaktioner. Här presenterar vi en metod för att ändra cellen ytbehandlar sialic acid uttryck med metabola glycoengineering med N- acetylmannosamine derivat.

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Bioteknik frågan 129 Sialic acid polysialic acid vätskekromatografi cellodling metaboliska glycoengineering metaboliska oligosackarid engineering
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