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Journal / Chemistry / Eş zamanlı ölçüm HDAC1 ve HDAC6 faaliyete HeLa…
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Eş zamanlı ölçüm HDAC1 ve HDAC6 faaliyete HeLa hücreleri kullanarak UHPLC-MS
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Eş zamanlı ölçüm HDAC1 ve HDAC6 faaliyete HeLa hücreleri kullanarak UHPLC-MS

Article DOI: 10.3791/55878-v • 09:20 min • August 10th, 2017
August 10th, 2017 •
*1, *1, 1, 1
1Section des Sciences Pharmaceutiques, Universités des Geneva–Lausanne (EPGL)
* These authors contributed equally

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Mevcut Yöntem birden çok yüzeylerde UHPLC-MS analizi tarafından Histon uyku (HDAC) HeLa hücreleri izoformu özgü inhibitörleri tanımlanmasını sağlar. Bu yaşam HDAC1 ve HDAC6 etkinliği yansıtmak üzere geliştirilen bir antikor-Alerjik yöntemdir tek-izoformu boş hücre deneyleri aksine hücre çevre.

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Kimya sayı: 126 HDAC1 HDAC6 inhibitörleri hücre tabanlı tahlil UHPLC-MS HeLa hücreleri
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