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Journal / Immunology and Infection / 流感病毒在小鼠感染模型中的研究
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Immunology and Infection

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JoVE Journal Immunology and Infection
流感病毒在小鼠感染模型中的研究
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流感病毒在小鼠感染模型中的研究

Article DOI: 10.3791/55898-v • 10:44 min • September 7th, 2017
September 7th, 2017 •
1, 1, 1
1Department of Microbiology and Immunology, University of Rochester School of Medicine and Dentistry

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甲型流感病毒 (IAVs) 是人类重要的呼吸道病原体。为了了解 IAVs 的致病性和对新疫苗方法进行临床前测试, 需要模仿人体生理学的动物模型。在这里, 我们描述的技术, 以评估 IAV 病机, 体液反应和疫苗的效果使用小鼠感染模型。

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免疫学 问题 127 甲型流感病毒 流感感染 小鼠 鼻腔接种 致病性 安全性 免疫原性 保护功效 病毒挑战 疫苗接种 体液反应
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