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Journal / Immunology and Infection / Influenza-A-Virus-Studien in einem Mausmodell der …
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Immunology and Infection

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JoVE Journal Immunology and Infection
Influenza-A-Virus-Studien in einem Mausmodell der Infektion
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Influenza-A-Virus-Studien in einem Mausmodell der Infektion

Article DOI: 10.3791/55898-v • 10:44 min • September 7th, 2017
September 7th, 2017 •
1, 1, 1
1Department of Microbiology and Immunology, University of Rochester School of Medicine and Dentistry

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Influenza A-Viren (IAVs) sind wichtige Humanpathogene Atemwege. Die Pathogenität von IAVs verstehen und neuartigen Impfstoff präklinischen Erprobung durchführen, sind Tiermodelle imitiert menschliche Physiologie erforderlich. Hier beschreiben wir Techniken zur Bewertung IAV Pathogenese, humorale Reaktionen und Wirksamkeit des Impfstoffes mit einem Maus-Modell der Infektion.

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Immunologie Ausgabe 127 Influenza A-Virus Influenza-Infektion Mäuse intranasale Impfung Pathogenität Sicherheit Immunogenität Schutz-Wirksamkeit virale Herausforderung Impfung humorale Reaktionen
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