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Journal / Cancer Research / Etablere to motstand mot EGFR-TKI og MØTTE-TKI i…
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JoVE Journal Cancer Research
Etablere to motstand mot EGFR-TKI og MØTTE-TKI i lunge Adenocarcinoma celler In Vitro med en 2-trinns doseopptrapping prosedyre
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Etablere to motstand mot EGFR-TKI og MØTTE-TKI i lunge Adenocarcinoma celler In Vitro med en 2-trinns doseopptrapping prosedyre

Article DOI: 10.3791/55967-v • 09:38 min • August 11th, 2017
August 11th, 2017 •
1, 1, 1,2, 1
1Institute of Molecular Oncology, Showa University, 2Center for Biotechnology, Showa University

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En i vitro metode for å etablere to motstand mot en EGFR-TKI og en MET-TKI i kreftcellene er beskrevet. Denne metoden er nyttig for utvikle behandlinger for pasienter med EGFR-mutasjoner, som viser sykdomsprogresjon til tross for EGFR-TKI behandling med MET-forsterkning. Det kan også endres for hemmere målretting andre molekyler.

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Kreftforskning problemet 126 lungekreft kjøpt to motstand EGFR-TKI MET-TKI lunge adenocarcinoma PC-9 celler gradvis dose opptrapping
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