Waiting
Login processing...

Trial ends in Request Full Access Tell Your Colleague About Jove
Journal / Genetics / High-resolution Melting PCR for Complement…
JoVE Journal
Genetics

This content is Open Access.

JoVE Journal Genetics
High-resolution Melting PCR for Complement Receptor 1 Length Polymorphism Genotyping
Using the GAL4-UAS System for Functional Genetics in Anopheles gambiae
Journal (Genetics)
Using the GAL4-UAS System for Functional Genetics in Anopheles gambiae
Semi-quantitative Detection of RNA-dependent RNA Polymerase Activity of Human Telomerase Reverse Transcriptase Protein
Journal (Genetics)
Semi-quantitative Detection of RNA-dependent RNA Polymerase Activity of Human Telomerase Reverse Transcriptase Protein
 

High-resolution Melting PCR for Complement Receptor 1 Length Polymorphism Genotyping: An Innovative Tool for Alzheimer's Disease Gene Susceptibility Assessment

Article DOI: 10.3791/56012-v • 07:26 min • July 18th, 2017
July 18th, 2017 •
1,2, 1,2, 1,2, 1,2, 3,4
1Department of Immunology, Reims University Hospitals, Robert Debré Hospital, 2Faculty of Medicine, LRN EA 4682, University of Reims Champagne-Ardenne, 3Department of Internal Medicine and Geriatrics, Reims University Hospitals, Maison Blanche Hospital, 4Faculty of Medicine, EA 3797, University of Reims Champagne-Ardenne

Chapters

Summary
Automatic Translation

Here, we describe an innovative method to determine complement receptor 1 (CR1) length polymorphisms for use in several applications, particularly the assessment of susceptibility to diseases such as Alzheimer's disease (AD). This method could be useful to better understand the role of CR1 isoforms in the pathogenesis of AD.

Tags

High-resolution Melting PCR Complement Receptor 1 Length Polymorphism Genotyping Alzheimer's Disease Gene Susceptibility Assessment Innovative Tool CR1 Isoforms Disease Pathogenesis Neuroscience Field Advantages Fresh Blood Samples Western Blots Proteinase K Lysis Buffer Ethanol Membrane Column
Read Article

Get cutting-edge science videos from JoVE sent straight to your inbox every month.

Waiting X
Simple Hit Counter