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Journal / Immunology and Infection / Generación de variantes de Escape de neutralizar…
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Immunology and Infection

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JoVE Journal Immunology and Infection
Generación de variantes de Escape de neutralizar anticuerpos Monoclonal del Virus de la Influenza
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Generación de variantes de Escape de neutralizar anticuerpos Monoclonal del Virus de la Influenza

Article DOI: 10.3791/56067-v • 07:55 min • August 29th, 2017
August 29th, 2017 •
1,2, 1,2, 1,2, 1,2, 3, 3, 1, 1
1Department of Microbiology, Icahn School of Medicine at Mount Sinai, 2Graduate School of Biomedical Sciences, Icahn School of Medicine at Mount Sinai, 3The Department of Medicine, Section of Rheumatology, The Knapp Center for Lupus and Immunology Research, The University of Chicago

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Se describe un método por el cual identificamos residuos críticos necesarios para la Unión de humanos o murinos anticuerpos monoclonales dirigidos a la hemaglutinina viral del virus de la gripe A. El protocolo puede ser adaptado a otras glicoproteínas de superficie del virus y sus correspondientes anticuerpos neutralizantes.

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Inmunología número 126 virus de la Influenza anticuerpos monoclonales variantes de escape microbiología virología
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