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Journal / Genetics / Laser Microirradiation In Vivo zellulären…
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JoVE Journal Genetics
Laser Microirradiation In Vivo zellulären Reaktionen auf einfache und komplexe DNA-Schäden zu studieren
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Laser Microirradiation In Vivo zellulären Reaktionen auf einfache und komplexe DNA-Schäden zu studieren

Article DOI: 10.3791/56213-v • 10:44 min • January 31st, 2018
January 31st, 2018 •
*1, *2, 2, 2, 2, 2,3,4, 1
1Department of Biological Chemistry, School of Medicine, University of California, Irvine, 2Beckman Laser Institute and Medical Clinic, University of California, Irvine, 3Department of Developmental and Cell Biology, School of Biological Sciences, University of California, Irvine, 4Department of Biomedical Engineering and Surgery, University of California, Irvine
* These authors contributed equally

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Das Ziel dieses Protokolls ist zu beschreiben, wie Laser Microirradiation verwenden, um verschiedene Arten von DNA-Schäden, einschließlich der relativ einfachen Strangbrüche und komplexen Schäden an DNA-Schäden Signal- und Reparatur Faktor Montage an Schaden Standorten in-vivo Studie zu induzieren .

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Genetik Ausgabe 131 Laser Microirradiation Laser in der Medizin DNA-Schäden DNA-Schäden Antwort DNA-Reparatur Poly (ADP-Ribose) Polymerase (PARP) komplexen Schäden strand Pausen Basisschaden
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