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Journal / Immunology and Infection / En metod för att bedöma Fc-medierad effektor…
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Immunology and Infection

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JoVE Journal Immunology and Infection
En metod för att bedöma Fc-medierad effektor funktioner induceras av influensa Hemagglutinin specifika antikroppar
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En metod för att bedöma Fc-medierad effektor funktioner induceras av influensa Hemagglutinin specifika antikroppar

Article DOI: 10.3791/56256-v • 04:47 min • February 23rd, 2018
February 23rd, 2018 •
1,2, 1, 1,2, 3
1Department of Microbiology, Icahn School of Medicine at Mount Sinai, 2Graduate School of Biomedical Sciences, Icahn School of Medicine at Mount Sinai, 3Department of Infectious Disease, J. Craig Venter Institute

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Vi beskriver en metod att mäta aktivering av Fc-medierad effektor funktioner av antikroppar som riktar den influensa virus hemagglutinin. Denna analys kan också anpassas för att bedöma monoklonala antikroppar eller polyklonala sera inriktning andra virala ytan glykoproteiner förmåga att inducera Fc-medierad immunitet.

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Immunologi fråga 132,
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