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Journal / Neuroscience / Transecção parcial nervo óptico em ratos: um…
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JoVE Journal Neuroscience
Transecção parcial nervo óptico em ratos
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Transecção parcial nervo óptico em ratos: um modelo estabelecido com uma nova abordagem operativa para avaliar secundária degeneração das células ganglionares da retina

Article DOI: 10.3791/56272-v • 13:12 min • October 15th, 2017
October 15th, 2017 •
1, 2, 2, 3, 3, 4, 4, 3
1Aier School of Ophthalmology, Central South University, Changsha, China, 2Institute of Immunology, Tsinghua University School of Medicine, Beijing, China, 3Beijing Tongren Eye Center, Beijing Tongren Hospital, Capital Medical University; Beijing Ophthalmology & Visual Sciences Key Laboratory, Beijing, China, 4Beijing Institute of Ophthalmology, Beijing Tongren Eye Center, Beijing Tongren Hospital, Capital Medical University; Beijing Ophthalmology & Visual Sciences Key Laboratory, Beijing, China

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Secundária degeneração das células ganglionares da retina (RGCs) comumente ocorre no glaucoma. Este estudo descreve uma abordagem inovadora e operativa para transecção parcial nervo óptico. O uso dessa abordagem operativa de economia de espaço amplia gama de aplicação do modelo e permite a exploração dos mecanismos de lesão secundária em RGCs de uma maneira nova.

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Neurociência edição 128 glaucoma células ganglionares da retina degeneração primária degeneração secundária transecção parcial nervo óptico artéria oftálmica
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