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JoVE Journal
Biochemistry

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个性化肽阵列在器官移植 HLA 抗体检测中的研究
 
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个性化肽阵列在器官移植 HLA 抗体检测中的研究

Article DOI: 10.3791/56278-v 08:07 min September 6th, 2017
September 6th, 2017

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Summary

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器官捐献者与受体对人白细胞抗原 (HLA) 序列的不匹配是器官移植中抗体介导的排斥反应的主要原因。在这里, 我们提出了使用自定义抗原阵列, 根据个别捐赠人的 hla 序列, 以探测 anti-donor hla 抗体在器官接受者。

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生物化学 问题 127 器官移植 抗体介导的移植排斥 (AMR) 人白细胞抗原 (hla) hla 错配 同种 抗原阵列 斑点合成
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