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JoVE Journal
Immunology and Infection

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非遗传表面修饰的素-生物素系统在牛分枝杆菌卡介苗中的外源抗原表达
 
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非遗传表面修饰的素-生物素系统在牛分枝杆菌卡介苗中的外源抗原表达

Article DOI: 10.3791/56421-v 10:11 min January 31st, 2018
January 31st, 2018

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Summary

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提出了一种新的细菌表面快速抗原显示技术, 它涉及表面法, 其次是暴露于与单体素融合的感兴趣的蛋白质。用选定抗原载入卡介苗, 成功地提高了其免疫原性, 表明表面修饰可以取代传统的遗传方法。

Tags

免疫学 问题 131 结核分枝杆菌 巨噬细胞 免疫反应 重组蛋白 T 细胞 抗原 生物素 素-生物素
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