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Cancer Research

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JoVE Journal Cancer Research
Analysere kommunikationen mellem monocytter og primær brystkræftceller i en ekstracellulære Matrix ekstrakt (ECME)-baseret tre-dimensionelle System
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Analysere kommunikationen mellem monocytter og primær brystkræftceller i en ekstracellulære Matrix ekstrakt (ECME)-baseret tre-dimensionelle System

Article DOI: 10.3791/56589-v • 10:55 min • January 8th, 2018
January 8th, 2018 •
*1,2, *1, 1
1Unidad de Investigación en Virología y Cáncer, Hospital Infantil de México Federico Gómez, 2Programa de Doctorado en Ciencias Biomédicas, Facultad de Medicina, Universidad Nacional Autónoma de México
* These authors contributed equally

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Her beskriver vi en tre-dimensionel kultur metode til at analysere morfologi af primær brystkræftceller, samt at studere deres direkte/indirekte interaktioner med monocytter og resultater som kollagen nedbrydning, immun celle rekruttering, celle invasion, og fremme af cancer-relaterede inflammation.

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Kræft biologi sag 131 tredimensionalt (3D) kultur ekstracellulære matrix ekstrakt (ECME) co kultur system tumor mikromiljø kommunikation brystkræft (BrC) monocytter tumor malignitet
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