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JoVE Journal Developmental Biology
Rápida detección de los fenotipos del neurodesarrollo en las células precursoras neuronales humanos (PNJ)
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Rápida detección de los fenotipos del neurodesarrollo en las células precursoras neuronales humanos (PNJ)

Article DOI: 10.3791/56628-v • 10:47 min • March 2nd, 2018
March 2nd, 2018 •
*1, *1, 1, 2, 3, 3, 4, 5, 2, 1
1Department of Neuroscience and Cell Biology, Rutgers Robert Wood Johnson Medical School, 2Center for Advanced Biotechnology and Medicine, Department of Neuroscience and Cell Biology, Rutgers Robert Wood Johnson Medical School, 3The Child Health Institute of NJ, Department of Obstetrics, Gynecology, and Reproductive Services, Rutgers Robert Wood Johnson Medical School, 4The Child Health Institute of NJ, Department of Neuroscience and Cell Biology, Rutgers Robert Wood Johnson Medical School, 5Department of Genetics, Rutgers University
* These authors contributed equally

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Desarrollo neurológico procesos como proliferación, migración y consecuencia del neurite son a menudo perturbados en enfermedades neuropsiquiátricas. Así, presentamos protocolos evaluar rápida y reproducible estos procesos del neurodesarrollo en NPCs humanos derivado de iPSC. Estos protocolos permiten la evaluación de los efectos relevantes factores de crecimiento y terapias en desarrollo de NPC.

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Biología del desarrollo número 133 neurodesarrollo biología del desarrollo células precursoras neuronales iPSC enfermedad cerebral autismo factores de crecimiento proliferación consecuencia del neurite migración celular
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