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Journal / Immunology and Infection / Vurdering af antistof-baserede lægemidler…
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Immunology and Infection

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JoVE Journal Immunology and Infection
Vurdering af antistof-baserede lægemidler virkninger på Murine knoglemarven og Peritoneal makrofag aktivering
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Vurdering af antistof-baserede lægemidler virkninger på Murine knoglemarven og Peritoneal makrofag aktivering

Article DOI: 10.3791/56689-v • 10:35 min • December 26th, 2017
December 26th, 2017 •
1, 1
1British Columbia Children's Hospital Research Institute, University of British Columbia

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Antistof-baserede lægemidler har revolutioneret behandling af inflammatoriske sygdomme. Ud over at have direkte virkninger på specifikke mål, kan antistoffer aktivere makrofager at blive anti-inflammatorisk. Denne protokol beskriver hvordan anti-inflammatoriske makrofag aktivering kan være vurderet in vitro ved hjælp af musen knoglemarv makrofager og in vivo med peritoneal makrofager.

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Immunologi spørgsmålet 130 makrofager knogle knoglemarv makrofager peritoneal makrofager antistof intravenøs immunglobulin biologics interleukin 10
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