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En kvantitativ Dot skamplet Assay for AAV titrering og dets anvendelse til funktionel vurdering af Adeno-associeret Virus forsamling-aktivering proteiner
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En kvantitativ Dot skamplet Assay for AAV titrering og dets anvendelse til funktionel vurdering af Adeno-associeret Virus forsamling-aktivering proteiner

Article DOI: 10.3791/56766-v • 14:49 min • June 12th, 2018
June 12th, 2018 •
1, 1, 1, 1,2
1Department of Molecular and Medical Genetics, Oregon Health & Science University, 2Department of Molecular Microbiology and Immunology, Oregon Health & Science University

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Dette manuskript detaljer en ligetil dot skamplet assay til kvantitering af adeno-associeret virus (AAV) titers og dens anvendelse til at studere rolle aktivering af forsamling proteiner (AAPs), en roman klasse af ikke-strukturelle virale proteiner, der findes i alle AAV serotyper, fremme samling af capsids stammer fra beslægtet og heterolog AAV serotyper.

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Biologi sag 136 Adeno-associeret virus (AAV) aktivering af forsamling protein (AAP) cross-komplementering kvantitative dot skamplet assay viral titer genterapi
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