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Un modello In Vivo murino nervo sciatico di invasione perineurale
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Un modello In Vivo murino nervo sciatico di invasione perineurale

Article DOI: 10.3791/56857-v • 09:55 min • April 23rd, 2018
April 23rd, 2018 •
*1, *1, 1, 1, 2, 3, 1
1Department of Surgery, Memorial Sloan Kettering Cancer Center, 2Molecular Cytology Core Facility, Memorial Sloan Kettering Cancer Center, 3Department of Radiation Oncology, Mount Sinai Hospital
* These authors contributed equally

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Descriviamo un modello murino in vivo di invasione perineurale iniettando le cellule tumorali pancreatiche syngeneic nel nervo sciatico. Il modello consente per la quantificazione del grado di invasione del nervo e appoggia la indagine dei meccanismi cellulari e molecolari dell'invasione perineurale.

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Ricerca sul cancro problema 134 invasione perineurale nervo sciatico cancro in vivo tumore PNI mouse l'adenocarcinoma pancreatico
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