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Immunology and Infection

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JoVE Journal Immunology and Infection
Laminar Flow-baseret Assays til at undersøge leukocyt ansættelse på kulturperler vaskulære celler og vedhængende blodplader
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Laminar Flow-baseret Assays til at undersøge leukocyt ansættelse på kulturperler vaskulære celler og vedhængende blodplader

Article DOI: 10.3791/57009-v • 08:50 min • April 9th, 2018
April 9th, 2018 •
1, 1, 1, 2, 1, 1, 1
1Department of Biochemistry, Cardiovascular Research Institute Maastricht (CARIM), Maastricht University, 2Department of Vascular Surgery, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University, School of Medicine

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Leukocytter interagere begærligt med vaskulære celler og blodplader efter fartøjet væg skade eller under betændelse. Her, beskriver vi en ligetil laminar flow-baseret analyse for at karakterisere de molekylære mekanismer, der ligger til grund for interaktioner mellem leukocytter og deres cellulære partnere.

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Immunologi og infektion spørgsmål 134 leukocyt adhæsion kaskade remodeling vaskulære betændelse blodplader integriner selectins kemokiner junctional vedhæftning molekyle
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