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Journal / Immunology and Infection / Ex Vivo Infecção da Mucosa Genital humano tecido…
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Immunology and Infection

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JoVE Journal Immunology and Infection
Ex Vivo Infecção da Mucosa Genital humano tecido linfoide e fêmea com vírus de imunodeficiência humana 1 e Histoculture
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Ex Vivo Infecção da Mucosa Genital humano tecido linfoide e fêmea com vírus de imunodeficiência humana 1 e Histoculture

Article DOI: 10.3791/57013-v • 11:14 min • October 12th, 2018
October 12th, 2018 •
1,2, 2, 2, 1, 2
1Department of Medicine Solna, Center for Molecular Medicine, Karolinska University Hospital, Karolinska Institutet, 2Section of Intercellular Interactions, Eunice Shriver National Institute of Child Health and Human Development, National Institutes of Health

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Infecção de tecidos humanos com vírus de imunodeficiência humana (HIV) ex vivo fornece um valioso modelo 3D da patogênese do vírus. Aqui, descrevemos um protocolo para processar e infectar amostras de tecido da amígdalas humanas e mucosa genital feminina com HIV-1 e mantê-las em cultura em uma interface líquido-ar.

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Imunologia e infecção questão 140 HIV vírus de imunodeficiência humana 1 histoculture tecido explantes ex vivo infecção patogênese tecido linfoide amígdalas mucosa cervical aparelho reprodutor feminino
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