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JoVE Journal Developmental Biology
Dreidimensionale entzündliche menschliches Gewebe Äquivalente der Gingiva
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Dreidimensionale entzündliche menschliches Gewebe Äquivalente der Gingiva

Article DOI: 10.3791/57157-v • 08:43 min • April 3rd, 2018
April 3rd, 2018 •
1, 2, 2
1Department of Pharmacology, The Nippon Dental University, 2Department of Oral and Maxillofacial Surgery, The Nippon Dental University Hospital

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Das Ziel des Protokolls ist eine entzündliche menschlichen Gingiva Modell in Vitrozu bauen. Dieses Gewebe Modell pflegt Co drei Arten von menschlichen Zellen, HaCaT Keratinozyten, gingival Fibroblasten und THP-1 Makrophagen, dreidimensionalen Bedingungen. Dieses Modell kann angewendet werden, für die Untersuchung von parodontaler Erkrankungen wie Gingivitis und Parodontitis.

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Entwicklungsbiologie Ausgabe 134 dreidimensionale Kultur Gingiva-Äquivalente gingival menschlichen Fibroblasten HaCaT-Zellen THP-1-Zellen Makrophagen Gewebetechnik entzündlichen Gewebe Modell Gingivitis Parodontitis Wundheilung Gewebe Regeneration
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