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En kanin Model af holdbare transgen udtryk i halsfedt til fælles halspulsåren Interposition Grafts
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En kanin Model af holdbare transgen udtryk i halsfedt til fælles halspulsåren Interposition Grafts

Article DOI: 10.3791/57231-v • 13:58 min • September 10th, 2018
September 10th, 2018 •
*1, *1, 1
1Department of Medicine, University of Washington School of Medicine
* These authors contributed equally

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Denne metode beskriver placeringen af interposition vene grafts i kaniner, transduktion af podninger, og opnåelsen af holdbare transgen udtryk. Dette giver mulighed for undersøgelse af fysiologiske og patologiske roller af transgener og deres proteinprodukter i podede vener, og afprøvning af genterapier for vene graft sygdom.

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Medicin sag 139 dyremodeller for sygdom hos mennesker åreforkalkning genterapi translationel undersøgelser kanin eksterne halsfedt fælles halspulsåren interposition vene graft karsygdom adenovirus helper-afhængige adenovirus.
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