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Geheel-hersenen segmentatie en verandering-punt analyse van anatomische hersenen MRI — toepassing in Premanifest de ziekte van Huntington
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Geheel-hersenen segmentatie en verandering-punt analyse van anatomische hersenen MRI — toepassing in Premanifest de ziekte van Huntington

Article DOI: 10.3791/57256-v • 09:06 min • June 9th, 2018
June 9th, 2018 •
1, 1, 2,3,4, 5, 1,6, 2,3,7
1The Russell H. Morgan Department of Radiology and Radiological Science, Johns Hopkins University School of Medicine, 2Center for Imaging Science, Johns Hopkins University, 3Institute for Computational Medicine, Johns Hopkins University, 4Department of Applied Mathematics and Statistics, Johns Hopkins University, 5Division of Neurobiology, Departments of Psychiatry, Neurology, Neuroscience and Pharmacology, and Program in Cellular and Molecular Medicine, Johns Hopkins University School of Medicine, 6F.M. Kirby Research Center for Functional Brain Imaging, Kennedy Krieger Institute, 7Department of Biomedical Engineering, Johns Hopkins University

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Dit witboek beschrijft een statistisch model voor volumetrische MRI data-analyse, waarmee de "verandering-point" wanneer de atrofie van de hersenen in premanifest de ziekte van Huntington begint. Geheel-brain mapping van de verandering-punten wordt bereikt op basis van hersenen volumes verkregen met behulp van een atlas gebaseerde segmentatie pijpleiding van T1-gewogen beelden.

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Geneeskunde kwestie 136 verandering-punt MRI atlas segmentatie granulariteit MRICloud premanifest HD
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