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Journal / Genetics / Manipulation der Diploidie in Caenorhabditis…
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Genetics

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JoVE Journal Genetics
Manipulation der Diploidie in Caenorhabditis elegans
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Manipulation der Diploidie in Caenorhabditis elegans

Article DOI: 10.3791/57296-v • 07:54 min • March 15th, 2018
March 15th, 2018 •
1, 1,2, 1, 1,3, 1,2,3
1Brooklyn College, Biology Department, City University of New York, 2The Graduate Center, Biology Department, City University of New York, 3Advanced Science Research Center, City University of New York

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Diese Methode ermöglicht die Generierung von tetraploiden und triploide Caenorhabditis Nematoden aus jeder diploiden Belastung. Polyploid Stämme von dieser Methode erzeugt wurden verwendet, um Chromosom Interaktionen in meiotischen Prophase zu untersuchen, und diese Methode ist nützlich für die Prüfung wichtiger Grundfragen in Zelle, Entwicklungsstörungen, evolutionär, und Krebsbiologie.

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Genetik Rec-8 Ausgabe 133 Polyploidie Caenorhabditis ElegansRNAi Meiose Endoreduplikation Vollständiggenom Vervielfältigung Genomgröße gen-Dosis biologische Skalierung genomische Instabilität
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