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JoVE Journal Cancer Research
Dobbelt virkningerne af melanom celle-afledte faktorer på knoglemarv adipocytter differentiering
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Dobbelt virkningerne af melanom celle-afledte faktorer på knoglemarv adipocytter differentiering

Article DOI: 10.3791/57329-v • 07:00 min • August 23rd, 2018
August 23rd, 2018 •
1, 2, 1, 3
1Department of Rheumatology, Ren Ji Hospital, School of Medicine, Shanghai Jiao Tong University, 2Department of Nephrology and Rheumatology, Yongchuan Hospital of Chongqing Medical University, 3Department of Medical Oncology, Fudan University Shanghai Cancer Center; Department of Oncology, Shanghai Medical College, Fudan University

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Her præsenterer vi en pålidelig og enkel todimensionale (2D) coculture system til at studere samspillet mellem tumorceller og knoglemarv adipocytter, hvilket afslører en dobbelt effekt af melanom celle-afledte faktorer på knoglemarv adipocytter differentiering og udgør også en klassisk metode for mekanistiske studier af knogle metastaser.

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Kræftforskning spørgsmålet 138 knoglemarv adipocyt knogle metastaser melanom coculture differentiering membran Indsæt
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