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Efeitos duplos de fatores derivado de células de Melanoma na diferenciação de adipócitos de medula óssea
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Efeitos duplos de fatores derivado de células de Melanoma na diferenciação de adipócitos de medula óssea

Article DOI: 10.3791/57329-v • 07:00 min • August 23rd, 2018
August 23rd, 2018 •
1, 2, 1, 3
1Department of Rheumatology, Ren Ji Hospital, School of Medicine, Shanghai Jiao Tong University, 2Department of Nephrology and Rheumatology, Yongchuan Hospital of Chongqing Medical University, 3Department of Medical Oncology, Fudan University Shanghai Cancer Center; Department of Oncology, Shanghai Medical College, Fudan University

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Aqui, apresentamos um sistema confiável e simples bidimensional coculture (2D) para estudar a interação entre as células do tumor e da medula óssea de adipócitos, que revela um duplo efeito de fatores derivado de células de melanoma em adipócitos a medula óssea diferenciação e também coloca um método clássico para o estudo mecanicista da metástase óssea.

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Cancer Research edição 138 adipócito de medula óssea metástase óssea melanoma coculture diferenciação inserção de membrana
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