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JoVE Journal Neuroscience
Isolamento dos capilares cerebrais do tecido do cérebro humano fresco
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Isolamento dos capilares cerebrais do tecido do cérebro humano fresco

Article DOI: 10.3791/57346-v • 06:35 min • September 12th, 2018
September 12th, 2018 •
1, 2, 2, 1, 1, 2, 1, 3, 2
1Sanders-Brown Center on Aging, Department of Pharmacology and Nutritional Sciences, University of Kentucky, 2Department of Pharmaceutical Sciences, College of Pharmacy, University of Kentucky, 3Department of Neuroscience, University of Kentucky

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Capilares do cérebro isolado do tecido do cérebro humano podem ser usados como um modelo pré-clínicos para estudar a função de barreira sob condições fisiológicas e fisiopatológicas. Aqui, apresentamos um protocolo otimizado para isolar os capilares do cérebro do tecido do cérebro humano fresco.

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Neurociência edição 139 neurociência neurovasculatura barreira hemato - encefálica os capilares do cérebro células endoteliais tecido cerebral humano
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