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Hurtig In Vivo evaluering af Adjuverendes cytotoksiske T-lymfocytter Generation kapaciteter for Vaccine udvikling
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Hurtig In Vivo evaluering af Adjuverendes cytotoksiske T-lymfocytter Generation kapaciteter for Vaccine udvikling

Article DOI: 10.3791/57401-v • 09:03 min • June 19th, 2018
June 19th, 2018 •
1, 1, 1, 1, 1, 1, 1, 1
1Department of Vaccinology and Applied Microbiology, Helmholtz Centre for Infection Research

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Vi præsenterer her en ansøgning om en standard immunologiske teknik (CFSE farves OT-jeg spredning) skal hurtigt overvåge adjuvans-medieret cytotoksiske T-lymfocytter (CTL) generation in vivo. Denne hurtig estimering af CTL kapacitet er nyttige for udviklingen af forebyggende vacciner mod intracellulære patogener samt terapeutiske kræft vacciner.

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Medicin sag 136 adjuverende virkning cross-præsentation og cross-priming ægalbumin cytotoksiske CD8+ T-celler OT-jeg spredning adoptiv overførsel hale vene injektion dræne lymfeknude
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