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Rumlige kvantificering af narkotika i lungetuberkulose læsioner af Laser fange Microdissection Liquid Chromatography massespektrometri (LCM-LC/MS)
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Rumlige kvantificering af narkotika i lungetuberkulose læsioner af Laser fange Microdissection Liquid Chromatography massespektrometri (LCM-LC/MS)

Article DOI: 10.3791/57402-v • 09:58 min • April 18th, 2018
April 18th, 2018 •
1, 1, 1, 1, 1
1Public Health Research Institute, New Jersey Medical School, Rutgers, The State University of New Jersey

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Her, beskriver vi en protokol, ved hjælp af laser fange microdissection kombineret med LC/MS analyse for at rumligt kvantificere drug distributioner inden for lungetuberkulose granulomer. Metoden har bred anvendelighed til at kvantificere drug koncentrationer i væv ved høj fysisk detalje.

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Medicin spørgsmål 134 tuberkulose narkotika distribution kvantificering laser fange microdissection væskekromatografi massespektrometri granuloma nekrose
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