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De Novo Generation af somatiske stamceller af YAP/TAZ
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De Novo Generation af somatiske stamceller af YAP/TAZ

Article DOI: 10.3791/57462-v • 13:05 min • May 7th, 2018
May 7th, 2018 •
1, 1, 1, 1, 1, 1
1Department of Molecular Medicine, University of Padua School of Medicine

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Tilgængeligheden af somatiske SCs er afgørende for regenerativ medicin, sygdom modellering og få indsigt i SC egenskaber. Præsenterer her vi eksperimentelle strategier til at omprogrammere, in vitro, differentieret voksne celler ind i deres tilsvarende udvideligt væv-specifikke stem/stamceller af forbigående udtryk for den enkelt transcriptional Co aktivator YAP.

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Biologi spørgsmålet 135 YAP/TAZ omprogrammering væv-specifikke stamceller mælkekirtlen bugspytkirtel organoids dedifferentiation
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