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Journal / Immunology and Infection / Injeksjoner av lipopolysakkarid i mus å…
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Immunology and Infection

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JoVE Journal Immunology and Infection
Injeksjoner av lipopolysakkarid i mus å etterligne av mikrobielle avledede produkter etter Intestinal barriere brudd
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Injeksjoner av lipopolysakkarid i mus å etterligne av mikrobielle avledede produkter etter Intestinal barriere brudd

Article DOI: 10.3791/57610-v • 08:24 min • May 2nd, 2018
May 2nd, 2018 •
1, 1, 1, 1, 1,2
1Department of Biomedicine, University of Basel, 2Division of Gastroenterology and Hepatology, University Hospital of Basel

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Her vises en protokoll å etterligne av bakteriell-avledet forbindelser etter intestinal barriere brudd. En lav sublethal dose av lipopolysakkarid ble injisert systemisk i mus, som var overvåket for 24 timer etter injeksjon. Uttrykk for pro-inflammatoriske cytokiner var fast bestemt på flere tidspunkt i milten og leveren kolon.

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Immunologi og infeksjon problemet 135 lipopolysakkarid endotoxemia kolitt inflammatorisk tarmsykdom barriere brudd cytokiner
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