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JoVE Journal Cancer Research
李 Fraumeni 症候群患者由来の誘導多能性幹細胞を用いた骨肉腫をモデリング
Co-culture of Glioblastoma Stem-like Cells on Patterned Neurons to Study Migration and Cellular Interactions
Journal (Cancer Research)
Co-culture of Glioblastoma Stem-like Cells on Patterned Neurons to Study Migration and Cellular Interactions
Microinjection of DNA Plasmid Mix into the Mouse Brain Ventricle (Video) | JoVE
Journal (Cancer Research)
Microinjection of DNA Plasmid Mix into the Mouse Brain Ventricle (Video) | JoVE
 
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李 Fraumeni 症候群患者由来の誘導多能性幹細胞を用いた骨肉腫をモデリング

Article DOI: 10.3791/57664-v • 08:52 min • June 13th, 2018
June 13th, 2018 •
1,2, 1, 1,3, 1, 4, 1, 1,2,5,6
1Department of Integrative Biology and Pharmacology, McGovern Medical School, The University of Texas Health Science Center at Houston, 2Graduate School of Biomedical Sciences, The University of Texas MD Anderson Cancer Center UTHealth, 3Department of Musculoskeletal Oncology, The First Affiliated Hospital of Sun Yat-sen University, 4Women's Health Institute, Cleveland Clinic Foundation, 5Center for Stem Cell and Regenerative Medicine, The Brown Foundation Institute of Molecular Medicine for the Prevention of Human Diseases, The University of Texas Health Science Center at Houston, 6Center for Precision Health, School of Biomedical Informatics and School of Public Health, The University of Texas Health Science Center at Houston

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ここでは、プロトコルを提案誘導多能性幹細胞 (Ips) の世代の李 Fraumeni シンドローム (LFS) 患者派生繊維芽細胞、間葉系幹細胞 (MSCs) 経由で Ips の分化から骨芽細胞、およびモデリングの体内にLFS 患者由来骨芽細胞を用いた腫瘍。

Tags

がん研究、問題 136、Ips、李 Fraumeni シンドローム、リプログラミング、分化、間葉系幹細胞、骨芽細胞、骨肉腫、異種移植
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