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Journal / Developmental Biology / Generation af første hjertet felt-lignende hjerte …
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Developmental Biology

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JoVE Journal Developmental Biology
Generation af første hjertet felt-lignende hjerte ophav og ventrikel-lignende Cardiomyocytes fra humane pluripotente stamceller
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Generation af første hjertet felt-lignende hjerte ophav og ventrikel-lignende Cardiomyocytes fra humane pluripotente stamceller

Article DOI: 10.3791/57688-v • 08:37 min • June 19th, 2018
June 19th, 2018 •
*1,2, *1, 1
1Sanford Burnham Prebys Medical Discovery Institute, 2Department of Bioengineering, University of California at San Diego
* These authors contributed equally

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Her beskriver vi en skalerbar metode, ved hjælp af en simpel kombination af Activin A og lentivirus-medieret Id1-overekspression, til at generere første hjertet felt-lignende hjerte ophav og ventrikel-lignende cardiomyocytes fra humane pluripotente stamceller.

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Udviklingsmæssige biologi sag 136 hjerte sygdom modellering stamcelle-baserede behandlinger første hjertet felt-lignende hjerte progenitorceller ventrikel-lignende cardiomyocytes Id1 hPSCs
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