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Journal / Cancer Research / Immunglobulin Gene Sequence Analysis i kronisk…
JoVE Journal
Cancer Research

This content is Open Access.

JoVE Journal Cancer Research
Immunglobulin Gene Sequence Analysis i kronisk lymfatisk leukemi
Expanding the Comprehension of the Tumor Microenvironment using Mass Spectrometry Imaging of Formalin-Fixed and Paraffin-Embedded Tissue Samples
Journal (Cancer Research)
Expanding the Comprehension of the Tumor Microenvironment using Mass Spectrometry Imaging of Formalin-Fixed and Paraffin-Embedded Tissue Samples
Somatic Genome-Engineered Mouse Models Using In Vivo Microinjection and Electroporation
Journal (Cancer Research)
Somatic Genome-Engineered Mouse Models Using In Vivo Microinjection and Electroporation
 
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Immunglobulin Gene Sequence Analysis i kronisk lymfatisk leukemi: Fra pasienten materiale til sekvens tolkning

Article DOI: 10.3791/57787-v • 09:02 min • November 26th, 2018
November 26th, 2018 •
*1, *2,3, 1, 4, 5, 6, 7, 2,3, 1,2, 8
1Institute of Applied Biosciences, Centre for Research and Technology Hellas, 2Department of Immunology, Genetics and Pathology, Science for Life Laboratory, Uppsala University, 3Department of Molecular Medicine and Surgery, Karolinska Institutet, 4Division of Immunology, Transplantation and Infectious, IRCCS San Raffaele Scientific Institute, 5Department of Immunology, Laboratory for Medical Immunology, Erasmus University Medical Center, 6Hematology Department, Nikea General Hospital, 7Assistance publique - Hôpitaux de Paris (AP-HP), Hopital Pitié-Salpêtrière, Department of Hematology, and UPMC University Paris 06, UMRS 1138, 8Division of Experimental Oncology, IRCCS Istituto Scientifico San Raffaele and Università Vita-Salute San Raffaele
* These authors contributed equally

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Summary
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Her presenterer vi en protokoll som detaljer de tekniske aspektene og viktige krav for å sikre robust IG genet sekvens analyse hos pasienter med kronisk lymfatisk leukemi (CLL), basert på erfaring av europeisk forskning initiativ på CLL (ERIC).

Tags

Kreftforskning problemet 141 kronisk lymfatisk leukemi (CLL) somatisk hypermutation (SHM) immunglobulin immunglobulin tunge variabel (IGHV) komplementaritet bestemme regionen 3 (CDR3) International ImMunoGeneTics informasjonssystem (IMGT)
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