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Journal / Bioengineering / Bioprintable 藻酸盐/明胶水凝胶…
JoVE Journal
Bioengineering

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JoVE Journal Bioengineering
Bioprintable 藻酸盐/明胶水凝胶 3D体外模型诱导细胞球形形成
Three-dimensional Cell Culture Model for Measuring the Effects of Interstitial Fluid Flow on Tumor Cell Invasion
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Three-dimensional Cell Culture Model for Measuring the Effects of Interstitial Fluid Flow on Tumor Cell Invasion
Procedure for the Development of Multi-depth Circular Cross-sectional Endothelialized Microchannels-on-a-chip
Journal (Bioengineering)
Procedure for the Development of Multi-depth Circular Cross-sectional Endothelialized Microchannels-on-a-chip
 
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Bioprintable 藻酸盐/明胶水凝胶 3D体外模型诱导细胞球形形成

Article DOI: 10.3791/57826-v • 16:20 min • July 2nd, 2018
July 2nd, 2018 •
*1, *2,3, 2, 4, 4, 3, 2,5
1Department of Mechanical Engineering, McGill University Montreal, 2Department of Bioengineering, McGill University Montreal, 3Department of Molecular Biology, Instituto Potosino de Investigación Científica y Tecnológica, A.C. (IPICyT), 4Department of Mining and Materials Engineering, McGill University Montreal, 5Department of Biomedical Engineering, McGill University Montreal
* These authors contributed equally

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我们开发了一种异种乳癌模型, 由永生化的肿瘤和成纤维细胞组成的 bioprintable 海藻酸盐/明胶 bioink。该模型概括体内肿瘤微环境, 促进多细胞肿瘤球体的形成, 对肿瘤的发生机制有深入的认识。

Tags

生物工程 问题 137 3D 生物打印 水凝胶 癌细胞 肿瘤球体 海藻酸盐 明胶
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