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Journal / Bioengineering / Hidrogel Bioprintable alginato/gelatina 3D In…
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Bioengineering

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JoVE Journal Bioengineering
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Hidrogel Bioprintable alginato/gelatina 3D In Vitro modelo sistemas inducen formación de glóbulo esferoide

Article DOI: 10.3791/57826-v • 16:20 min • July 2nd, 2018
July 2nd, 2018 •
*1, *2,3, 2, 4, 4, 3, 2,5
1Department of Mechanical Engineering, McGill University Montreal, 2Department of Bioengineering, McGill University Montreal, 3Department of Molecular Biology, Instituto Potosino de Investigación Científica y Tecnológica, A.C. (IPICyT), 4Department of Mining and Materials Engineering, McGill University Montreal, 5Department of Biomedical Engineering, McGill University Montreal
* These authors contributed equally

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Hemos desarrollado un modelo de cáncer de mama heterogéneos consistiendo en las células fibroblastos y tumor inmortalizadas encajadas un bioink de alginato/gelatina de bioprintable. El modelo recoge el microambiente tumoral de en vivo y facilita la formación de esferoides multicelulares tumor, dando la penetración en los mecanismos de conducción tumorigenesis.

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Bioingeniería número 137 bioprinting 3D hidrogel las células cancerosas esferoides tumorales alginato gelatina
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