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Journal / Bioengineering / Bioprintable alginat/Gelatin Hydrogel 3D In Vitro …
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Bioengineering

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JoVE Journal Bioengineering
Bioprintable alginat/Gelatin Hydrogel 3D In Vitro modellsystem framkalla Cell sfäroid bildas
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Bioprintable alginat/Gelatin Hydrogel 3D In Vitro modellsystem framkalla Cell sfäroid bildas

Article DOI: 10.3791/57826-v • 16:20 min • July 2nd, 2018
July 2nd, 2018 •
*1, *2,3, 2, 4, 4, 3, 2,5
1Department of Mechanical Engineering, McGill University Montreal, 2Department of Bioengineering, McGill University Montreal, 3Department of Molecular Biology, Instituto Potosino de Investigación Científica y Tecnológica, A.C. (IPICyT), 4Department of Mining and Materials Engineering, McGill University Montreal, 5Department of Biomedical Engineering, McGill University Montreal
* These authors contributed equally

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Vi utvecklade en heterogen bröst cancer modell bestående av förevigade tumör och fibroblast celler inbäddade i en bioprintable alginat/gelatin bioink. Modellen recapitulates den i vivo tumör närmiljön och underlättar bildningen av flercelliga tumör spheroids, ger inblick i drivkrafterna bakom uppkomst.

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Bioteknik fråga 137 3D bioprinting hydrogel cancerceller tumör spheroids alginat gelatin
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