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Nasal potentielle forskel at kvantificere Trans-epitelial Ion Transport i mus
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Nasal potentielle forskel at kvantificere Trans-epitelial Ion Transport i mus

Article DOI: 10.3791/57934-v • 08:55 min • July 4th, 2018
July 4th, 2018 •
1, 1
1Louvain Center for Toxicology and Applied Pharmacology (LTAP), Institut de Recherche Expérimentale et Clinique (IREC), Université Catholique de Louvain

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Vi præsenterer her, en protokol for at måle nasal spændingsforskel i mus. Testen kvantificerer funktion af transmembrane ion transportvirksomheder som cystisk fibrose transmembrane ledningsevne regulator og epitelial natrium-kanal. Det er værdifuldt at evaluere effekten af nye terapier for cystisk fibrose.

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Biologi sag 137 cystisk fibrose CFTR ENaC nasal spændingsforskel ion transport musemodeller af sygdom biomarkør for terapeutisk virkning diagnose
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