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Journal / Immunology and Infection / Avaliação das respostas de células T Zika vírus…
JoVE Journal
Immunology and Infection

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JoVE Journal Immunology and Infection
Avaliação das respostas de células T Zika vírus específicos em órgãos Immunoprivileged de infectados Ifnar1- / - ratos
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Avaliação das respostas de células T Zika vírus específicos em órgãos Immunoprivileged de infectados Ifnar1- / - ratos

Article DOI: 10.3791/58110-v • 10:01 min • October 17th, 2018
October 17th, 2018 •
*1,2, *2, *3, 1,2, 4, 2, 5, 6, 3, 1,2,4,6, 1,2
1School of Laboratory Medicine and Life Sciences, Wenzhou Medical University, 2NHC Key Laboratory of Medical Virology and Viral Diseases, National Institute for Viral Disease Control and Prevention, Chinese Center for Disease Control and Prevention, 3State Key Laboratory of Agrobiotechnology, College of Biological Sciences, China Agricultural University, 4Research Network of Immunity and Health (RNIH), Beijing Institutes of Life Science, Chinese Academy of Sciences, 5Laboratory Animal Center, Chinese Center for Disease Control and Prevention, 6CAS Key Laboratory of Pathogenic Microbiology and Immunology, Institute of Microbiology, Chinese Academy of Sciences
* These authors contributed equally

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Um protocolo para avaliar as respostas de células T antígeno-específicas nos órgãos immunoprivileged do Ifnar1- / - modelo murino para a infecção de vírus (ZIKV) Zika é descrito. Este método é essencial para investigar os mecanismos celulares da proteção e imunopatogênese das vacinas ZIKV e também é valioso para sua avaliação de eficácia.

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Imunologia e infecção questão 140 vírus Zika pilha de T antígeno-específicas immunoprivileged órgãos vacinação tetrâmero
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