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Journal / Immunology and Infection / Evaluación de respuestas de células T Zika…
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Immunology and Infection

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JoVE Journal Immunology and Infection
Evaluación de respuestas de células T Zika Virus-específica en Immunoprivileged órganos de ratones- / - Ifnar1 infectados
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Evaluación de respuestas de células T Zika Virus-específica en Immunoprivileged órganos de ratones- / - Ifnar1 infectados

Article DOI: 10.3791/58110-v • 10:01 min • October 17th, 2018
October 17th, 2018 •
*1,2, *2, *3, 1,2, 4, 2, 5, 6, 3, 1,2,4,6, 1,2
1School of Laboratory Medicine and Life Sciences, Wenzhou Medical University, 2NHC Key Laboratory of Medical Virology and Viral Diseases, National Institute for Viral Disease Control and Prevention, Chinese Center for Disease Control and Prevention, 3State Key Laboratory of Agrobiotechnology, College of Biological Sciences, China Agricultural University, 4Research Network of Immunity and Health (RNIH), Beijing Institutes of Life Science, Chinese Academy of Sciences, 5Laboratory Animal Center, Chinese Center for Disease Control and Prevention, 6CAS Key Laboratory of Pathogenic Microbiology and Immunology, Institute of Microbiology, Chinese Academy of Sciences
* These authors contributed equally

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Se describe un protocolo para evaluar las respuestas de células T antígeno específicas en los órganos de immunoprivileged del Ifnar1- / - modelo murino para la infección del virus (ZIKV) Zika. Este método es fundamental para la investigación de los mecanismos celulares de la protección y la inmunopatogénesis de las vacunas ZIKV y también es valiosa para la evaluación de su eficacia.

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Inmunología e infección número 140 Zika virus la célula de T antígeno-específica vacunación immunoprivileged órganos tetrámero
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