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Journal / Immunology and Infection / Utvärdering av Zika Virus-specifika T-cell svar i …
JoVE Journal
Immunology and Infection

This content is Open Access.

JoVE Journal Immunology and Infection
Utvärdering av Zika Virus-specifika T-cell svar i Immunoprivileged organ av infekterade Ifnar1- / - möss
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Utvärdering av Zika Virus-specifika T-cell svar i Immunoprivileged organ av infekterade Ifnar1- / - möss

Article DOI: 10.3791/58110-v • 10:01 min • October 17th, 2018
October 17th, 2018 •
*1,2, *2, *3, 1,2, 4, 2, 5, 6, 3, 1,2,4,6, 1,2
1School of Laboratory Medicine and Life Sciences, Wenzhou Medical University, 2NHC Key Laboratory of Medical Virology and Viral Diseases, National Institute for Viral Disease Control and Prevention, Chinese Center for Disease Control and Prevention, 3State Key Laboratory of Agrobiotechnology, College of Biological Sciences, China Agricultural University, 4Research Network of Immunity and Health (RNIH), Beijing Institutes of Life Science, Chinese Academy of Sciences, 5Laboratory Animal Center, Chinese Center for Disease Control and Prevention, 6CAS Key Laboratory of Pathogenic Microbiology and Immunology, Institute of Microbiology, Chinese Academy of Sciences
* These authors contributed equally

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Ett protokoll för att utvärdera antigen-specifika T-cell svar i immunoprivileged organ Ifnar1- / - murina modellen för Zika virus (ZIKV) infektionen beskrivs. Denna metod är avgörande för att utreda de cellulära mekanismerna för skydd och immunpatogenes ZIKV vacciner och är också värdefull för deras effekt utvärdering.

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Immunologi och infektion fråga 140 zikavirus antigen-specifika T-cell vaccination immunoprivileged organ tetramer
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